Can Mark Cuban’s Pharmacy Save You Money?

Discover how Mark Cuban's Cost Plus Drugs pharmacy is slashing prescription costs with transparent pricing and generics.

By Medha deb
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Can Mark Cuban’s Pharmacy Save You Money on Prescriptions?

Mark Cuban, the billionaire entrepreneur known for Shark Tank and owning the Dallas Mavericks, launched the Mark Cuban Cost Plus Drug Company in January 2022 to tackle skyrocketing prescription drug prices in America. This online pharmacy focuses on generic medications, pricing them at manufacturing cost plus a flat 15% markup, a $3 pharmacist fee, and $5 shipping. The model cuts out middlemen like pharmacy benefit managers (PBMs), which often inflate costs even for cheap generics.

With prescription drug spending in the U.S. reaching hundreds of billions annually, and millions skipping doses due to cost, Cuban’s venture promises real relief, especially for uninsured or high-deductible plan holders. A Harvard study estimated Medicare could have saved $3.6 billion in 2020 on 77 generics if using Cost Plus pricing—a 37% reduction on $9.6 billion spent. But does it work for everyday users? Let’s break it down.

What Is the Mark Cuban Cost Plus Drug Company?

The Mark Cuban Cost Plus Drug Company (costplusdrugs.com) is a direct-to-consumer online pharmacy emphasizing transparency. Unlike traditional pharmacies where prices are opaque and markups can exceed 1,000%, Cost Plus reveals every component: the actual wholesale acquisition cost from manufacturers, plus 15% for operations, $3 for pharmacy dispensing, and $5 flat-rate shipping via partner Truepill.

Launched amid frustration with PBMs—who negotiate rebates but often keep patients in the dark—Cost Plus vertically integrates to bypass these intermediaries. CEO Alex Oshmyansky has called out ‘bad actors’ in the supply chain preventing affordable access. As of recent expansions, it offers over 800 generics for conditions like cancer, diabetes, heart disease, mental health, and infections.

This isn’t charity; it’s business. Cuban funds it personally, aiming to scale by proving generics can be profitable without gouging. Early adopters report dramatic savings, like one uninsured patient dropping from $1,000–$1,200 monthly to under $100 for blood pressure, cholesterol, and diabetes meds.

How Does Pricing Work at Cost Plus Drugs?

Transparency defines the model. Take colchicine, a gout treatment (generic Colcrys): manufacturing cost is $4.80 for 30 days. Cost Plus adds 15% ($0.72), $3 fee, totaling $8.52 before $5 shipping—versus retail $176. Fluoxetine (generic Prozac, antidepressant): $3.90 vs. $21.90 retail. Albendazole (parasitic infections): $33 vs. $437.

DrugUseCost Plus Price (30-day)Retail Avg.Savings
ColchicineGout$8.70 (incl. fee)$17695%
FluoxetineDepression$3.90$21.9082%
AlbendazoleParasites$33$43792%
Generic GLP-1 (e.g., for diabetes)Weight/diabetesVaries, often <$100/mo$1,000+90%+

Note: Prices exclude shipping; actual totals add $5–$8. Data from 2022 reports, subject to change.

For a 90-day supply, savings compound. Medicare’s potential $3.6B save highlights scale: 37% off 77 drugs. A PMC study found patients could save ~$5 per script on 11.8% of 124 generics in 2019 vs. insurance, with uninsured benefiting most.

Who Can Benefit Most from Cost Plus Drugs?

  • Uninsured or underinsured: No insurance? Full savings. One doctor reported a patient resuming full meds after costs plummeted.
  • High-deductible plans: Before deductible, pay full price—Cost Plus often beats it.
  • Generic users: 90% of scripts are generics; Cost Plus excels here.
  • Chronic conditions: Diabetes, heart, mental health drugs see huge cuts.

Limitations: Insured with good copays may pay less via coverage. PMC analysis: insurance cheaper for most, but 11.8% of scripts (esp. uninsured) save via Cost Plus. Only 26% of ‘expensive’ generics available as of 2023.

How to Order From Mark Cuban’s Pharmacy

  1. Check availability: Search costplusdrugs.com for your med (150+ initially, now 800+).
  2. Get prescription: Ask doctor to e-prescribe directly to Cost Plus (use their pharmacy address).
  3. Upload/create account: No insurance needed; pay out-of-pocket.
  4. Shipped: $5 flat via Truepill, 30/90-day supplies.

No coupons accepted. Brand-name? Ask doc for generic switch. Expansions planned.

Pros and Cons of Cost Plus Drugs

ProsCons
Transparent, low prices on genericsLimited to generics (no brands yet)
Cuts middlemen, huge savings potential$5 ship + $3 fee adds up for small orders
Direct from manufacturer costsMay not beat insurance copays for all
Expands access for uninsuredNot all drugs available
Medicare-scale savings provenMail-order only (no walk-in)

Experts praise disruption of PBMs but note brand drugs (patented, pricier) are the real crisis—Cost Plus focuses on post-patent generics.

Frequently Asked Questions (FAQs)

Does Cost Plus Drugs accept insurance or coupons?

No, it’s cash-pay only, no coupons. Designed for transparent out-of-pocket savings.

How much is shipping?

$5 flat rate via Truepill, regardless of order size.

What if my drug isn’t available?

Currently 800+ generics; expanding. Ask doctor for generic alternative.

Is it cheaper than my insurance?

Often for uninsured/high-deductible; study shows savings on 11.8% of generics, esp. uninsured.

Can I get brand-name drugs?

No, focuses on generics. Brands drive high costs via patents/PBM rebates.

How does it compare to other online pharmacies?

More transparent than most; similar to DiRx/HealthWarehouse but Cuban-backed with aggressive pricing.

Is Cost Plus Solving America’s Drug Price Crisis?

Partially. Gallup/West Health: 18M Americans skip meds yearly due to cost. Cost Plus delivers on generics (90% of market), sidestepping PBMs who inflate even cheap drugs. But brands—rising yearly—remain untouched, as rebates flow via PBMs/insurers, indirectly lowering premiums.

UCSD’s Inma Hernandez notes opacity in rebates: patients pay full, middlemen pocket shares. NYU’s José Pagán highlights PBM criticism for upping generic prices. Cost Plus proves vertical integration works, but scaling to brands/PBM dominance is the ‘elephant in the room.’

Patient stories shine: unemployed woman back on regimen. Medicare sims show billions saved. For many, it’s a game-changer; for others, supplemental to insurance.

Other Ways to Save on Prescriptions

  • GoodRx/Walgreens coupons for discounts.
  • Switch to generics/90-day supplies.
  • Patient assistance programs (e.g., via NeedyMeds).
  • Compare pharmacies (Walmart $4 lists).
  • Amazon Pharmacy/Prime savings on generics.

Cuban’s model pressures the system toward transparency. As it grows, expect more drugs, possibly brands.

References

  1. Can Mark Cuban’s pharmacy save you money on prescriptions? — Las Vegas Review-Journal. 2022-06-23. https://www.reviewjournal.com/life/health/can-mark-cubans-pharmacy-save-you-money-on-prescriptions-2597349/
  2. A doctor says Mark Cuban’s online pharmacy saved a patient over… — Fortune. 2022-08-14. https://fortune.com/2022/08/14/mark-cuban-cost-plus-drugs-online-pharmacy-doctors-prescriptions-money-healthcare/
  3. Mark Cuban’s pharmacy startup is actually making drugs less expensive… — West Health. N/A. https://westhealth.org/news/mark-cubans-pharmacy-startup-is-actually-making-drugs-less-expensive-its-still-working-on-solving-the-real-problem/
  4. Patient-Level Savings on Generic Drugs Through the Mark Cuban… — PMC (NIH). 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11179122/
  5. Online Pharmacy Comparison: Their Features, Pros and Cons — The Penny Hoarder. N/A. https://www.thepennyhoarder.com/save-money/online-pharmacy-comparison/
Medha Deb is an editor with a master's degree in Applied Linguistics from the University of Hyderabad. She believes that her qualification has helped her develop a deep understanding of language and its application in various contexts.

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